Introduction of the mammalian immune system and its function in defense against pathogens. Overview of infections diseases and causative agents. Virulence mechanisms of viral, bacterial and fungal pathogens. Detection, therapy, prevention of infectious diseases.
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*Content of practical course*
Two weeks full day lab course in BL2 labs of the Div. Microbiology for work with bacterial pathogens.
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Invasion of eukaryotic cells by bacteria
Intracellular propagation
Adhesion
Regulation of virulence genes
current methods of genetic manipulation
Diversity: Proteomics for identification of specific virulence factors